Ophiuca

Ophiuca is based of the serpent-tamer constellation, Ophiuchus. She form is that of a dark purple snake, she has the power to control snakes. Her seiyū is Kaoru Morota and her English voice actress is Dorothy Elias-Fahn.

In the game, because of her involvements with numerous FM-ian incidents, caused her parents to transfer her to a new school. She keeps this painful news away from her friends. At the mall, she observes Geo and Sonia while they attend a jungle exhibit, and tailed them out of jealously. There she has an unexpected run-in with her parents, and the confrontation prompts Ophiuca to appear before her. Ophiuca promises to make Luna's parents pay, and Luna allows Ophiuca to invade her heart, merging the together to create Ophiuchus Queen (オヒュカス・クイーン, Ohyukasu Kuīn). Queen Ophiuca holds Luna's parents hostage demanding Omega-Xis hand over the Andromeda Key. Mega Man eventually beats Queen Ophiuca, but she tries to persuade Omega-Xis to hand over the key so they may use its power together. Omega-Xis refuses, and Ophiuca is defeated by Gemini on a whim

In the anime, Luna suspects that MegaMan is unaware of his secret identity. It was this weakness that she is targeted by "Ophiuchus" during one of Sonia's concerts, taking advantage of Luna's desire to see her hero and her jealousy over Lyra Note, who she believes may be romantically involved with Mega Man. Luna allows Ophiuca to invade her heart, merging the together to create Ophiuchus Queen. MegaMan and Harp Note team up and defeat her. Unfortunately, Ophiuchus escapes.

Later, Ophiuchus takes on the form of W Luna while gathering minus energy to recreate the Andromeda Key. During this time, Ophiuchus often bickered with other FM-ians over how to spend money, and she herself also developed a love of shopping. Eventually, Ophiuchus is deleted by Gemini Spark in order to fill the Andromeda Key